The growing body of evidence supporting the beneficial effects of physical activity on Alzheimer's disease highlights its potential as a powerful intervention for both prevention and management. Regular physical activity not only reduces the risk of developing AD but also plays a crucial role in slowing the progression of cognitive decline in those already diagnosed with the disease. Key to this benefit is the role of PA in enhancing neuroplasticity, improving vascular health, and reducing neuroinflammation—factors all linked to the development and progression of AD. Studies have shown that even modest amounts of physical activity can increase the size of brain regions critical for memory and cognitive function, making it a crucial aspect of brain health at all ages.

For individuals with mild cognitive impairment (MCI) or early-stage AD, PA provides notable benefits. Aerobic and resistance exercises have been shown to improve cognitive performance, particularly executive functions and memory. PA also enhances physical health, reduces symptoms of depression and anxiety, and fosters social engagement, collectively improving the quality of life.

A growing body of research supports the significant role of physical activity (PA) in reducing the risk of Alzheimer’s disease (AD). A systematic review of 24 longitudinal studies found that the majority of studies (18 out of 24) reported that regular physical activity was associated with a reduced risk of developing AD. This effect was particularly strong for leisure-time physical activity, which includes activities like walking, swimming, aerobics, cycling, and gardening. These activities not only improve cardiovascular health but also promote cognitive functions and enhance brain health, providing a broad range of benefits.